Stein, M.D., Shailaja Suryawanshi, Ph.D., Frans Van de Werf, M.D., Ph.D., Eric D. Peterson, M.D., M.P.H., and Rury R. Holman, M.B., Ch.B. For the TECOS Research Group: Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes Great glycemic control among sufferers with type 2 diabetes reduces the risk of diabetes-related microvascular complications.1-3 Many antihyperglycemic agents are licensed for the treating type 2 diabetes, but questions regarding the long-term cardiovascular safety of some of these agents have already been raised.4,5 International regulatory agencies have responded by needing that new antihyperglycemic agents not only show glucose-lowering ability but also are not associated with clinically meaningful increases in rates of major adverse cardiovascular events.6,7 Sitagliptin, an orally administered dipeptidyl peptidase 4 inhibitor, prolongs the action of incretin hormones, including glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide, simply by inhibiting their breakdown.Based on your condition, your doctor can recommend the proper medication for your unique type of depression, whether severe or mild. Since the marketplace is full with anti depression medication, it is vital to note that by no means take over the counter anti unhappiness pills/ medication. This is risky and not meant to end up being experimented with. In the event you take the incorrect medicines or in the incorrect dosages, there can be enormous disasters. Always medicate yourself only once you consulted a physician.