Trussell, M.D., Dana Ohl, M.D., Yufeng Jin, M.S., Nanette Santoro, M.D., Esther Eisenberg, M.D., M.P.H., and Heping Zhang, Ph.D. For the NICHD Reproductive Medicine Network: Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility.. Michael P. Diamond, M.D., Richard S. Legro, M.D., Christos Coutifaris, M.D., Ph.D, Ruben Alvero, M.D., Randal D. Robinson, M.D., Peter Casson, M.D., Gregory M. Christman, M.D., Joel Ager, Ph.D., Hao Huang, M.D., M.P.H., Karl R. Hansen, M.D., Ph.D., Valerie Baker, M.D., Rebecca Usadi, M.D., Aimee Seungdamrong, M.D., G. Wright Bates, M.D., R.The entire results of a big trial might disguise a worthwhile clinical benefit in smaller subpopulations of patients. However, no proof was found by us that the result of revascularization differed among individuals with varying levels of renal disease, with the serum creatinine level, approximated glomerular filtration rate, intensity of stenosis, and renal duration used as variables. A significant post hoc subgroup evaluation of sufferers for whom many clinicians currently advocate revascularization also showed no significant difference in outcome between patients with severe renal-artery stenosis and those without such serious disease.