Severe acute toxicity was defined as the price of grade 3 or 4 4 illness, stomatitis, febrile neutropenia, or all of these events, according to the National Cancers Institute Common Toxicity Criteria. Statistical Analysis The analysis design was based on a test of noninferiority of cisplatin in comparison with cisplatin plus doxorubicin for the primary end point . The process stated that cisplatin will be considered to be noninferior to cisplatin plus doxorubicin if the rate of complete resection had not been decreased by a lot more than 10 %age factors from the 90 %age factors anticipated with cisplatin plus doxorubicin. This 10 percent margin was useful for interim monitoring. Provided the rarity of the tumor and the anticipated annual recruitment of 30 to 35 patients, it was recognized that a tighter noninferiority margin could not be prepared.In July, the Associated Press found West Virginia was spending even more per capita than any additional state to market awareness of the law and the new health care exchanges, with $17.1 million. That amounts to $9.23 per resident and was 11th among the states altogether spending . The Associated Press: Illinois Unveils Wellness Marketplace Ads Illinois officials plan to start a long-delayed, $33 million marketing campaign to inform occupants about a new health insurance market Tuesday, the ads first appearing on the same day industry goes live with information on benefits obtainable under President Barack Obama's healthcare law.