This can be achieved by inducing vomiting or by placing a big tube through the person`s mouth and into the stomach, putting liquid in and then pumping it out . N-acetylcysteine : NAC may be the antidote for toxic acetaminophen overdose. It is distributed by mouth generally. The medication includes a foul smell but may be blended with juice or other flavorings to create it taste better. If the individual cannot take NAC by mouth, a tube might be placed through the mouth and into the stomach to greatly help administer it. If offering NAC by this method is not possible, the doctor might want to give it by IV. NAC is normally given for 20-72 hours. Activated charcoal: Activated charcoal can be given by mouth area to bind any drug staying in the gastrointestinal system..Siminovitch, M.D.: Major Biliary Cirrhosis Connected with HLA, IL12A, and IL12RB2 Variants Primary biliary cirrhosis may be the most common autoimmune liver disease, affecting up to at least one 1 in 1000 women over 40 years.1 Treatment because of this chronic cholestatic condition continues to be empirical.2 The granulomatous destruction of interlobular bile ducts that characterizes main biliary cirrhosis is nearly always associated with antimitochondrial antibodies specific for the E2 subunit of the pyruvate dehydrogenase complex.4-6 A genetic predisposition for principal biliary cirrhosis has been revealed by analysis of both aggregation data from families and concordance data from twins.