Dentures offer quick missing tooth solutions, and restore the proper type and function of the smile. Denture wearers shall be able to eat, smile, and consult with ease even after suffering from multiple tooth loss. However, removable dentures will lose their tight fit in the mouth. The reason being of jawbone deterioration, which happens when the bone is not stimulated by tooth roots. As the jawbone gets thinner, the dentures become looser and start to become painful to make use of. So long as the nagging issue of bone deterioration isn’t resolved, the dentures will continue to become more difficult and even more embarrassing to use with the passage of additional time.The trials used similar protocol-specified procedures for original classification and collection of fractures. We examined the fractures, using identical methods for the three research, to identify and describe femoral-shaft assess and fractures atypical features when possible.6 were recruited16 and randomly assigned to get daily alendronate or placebo and were followed for 3 to 4 4.5 years.16-18 Relevant data included demographic characteristics, bone mineral density scores, the use of concomitant medications, previous osteoporosis therapies, adverse occasions, and levels of biochemical markers of bone turnover. FIT Long-Term Extension Trial Following the FIT trial ended, women were offered open-label alendronate for 1 year, and a randomized extension trial began.19 A total of 1099 women who were originally assigned to get alendronate underwent another randomization to get alendronate at a daily dose of 5 mg or 10 mg or placebo and were followed for 5 more years.